For right now, it gets me by
©
usmle1mikmonics:

diseasesinthreewords:
Posttranslational. The defective protein (a transmembrane conductance regulator) gets translated by mRNA and ribosomes. But the regular modifications that happen after translation fail (folding and glicosilation). Phenilalaline is the aminoacid deleted at position 508. Chromo 7 = Cystic 7ibrosis (turn F around) AR
Staph aureus. Sure, Pseudomonas is the more famous of the bacteria causing infections in CF patients. But it only leads the number of cases after age 10, before then, S. aureus is king.
Malabsorption. Very common to see malnutrition and poor growth and development. Hypoproteinemia and fat-soluble vitamin deficiencies are also classical.

cYSTIC FIBROSIS

N-acetylcysteine (cleaves disulfide bonds in mucus)  + antipseudomonal prophylaxis (tobramycin/azithromycin) 

Bronchiectasis, meconium ileus, nasal polyps, failure to thrive, \
Cystic fibrosis: presenting signs CF PANCREAS:
Chronic cough and wheezing
Failure to thrive
Pancreatic insufficiency (symptoms of malabsorption like steatorrhea)
Alkalosis and hypotonic dehydration
Neonatal intestinal obstruction (meconium ileus)/ Nasal polyps
Clubbing of fingers/ Chest radiograph with characteristic changes
Rectal prolapse
Electrolyte elevation in sweat, salty skin
Absence or congenital atresia of vas deferens
Sputum with Staph or Pseudomonas (mucoid)
“CF PANCREAS”
 Chronic respiratory diseases occur*
 Failure to thrive, poor weight gain
 Pancreatic exocrine and endocrine insufficiency, Pulmozyme as treatment
 Autosomal recessive inheritance, metabolic Alkalosis
 Neonatal intestinal obstruction, meconium ileus, intussusception, volvulus
 Clubbing of fingers, Cholestasis, biliary Cirrhosis, …**
 Rectal prolapse
 Electrolyte excess in sweat like sweat Na+ and Cl-
 Azoospermia and infertility
 Staph aureus and pSeudomonas in sputum, Salty sweat

usmle1mikmonics:

diseasesinthreewords:

  1. Posttranslational. The defective protein (a transmembrane conductance regulator) gets translated by mRNA and ribosomes. But the regular modifications that happen after translation fail (folding and glicosilation). Phenilalaline is the aminoacid deleted at position 508. Chromo 7 = Cystic 7ibrosis (turn F around) AR
  2. Staph aureus. Sure, Pseudomonas is the more famous of the bacteria causing infections in CF patients. But it only leads the number of cases after age 10, before then, S. aureus is king.
  3. Malabsorption. Very common to see malnutrition and poor growth and development. Hypoproteinemia and fat-soluble vitamin deficiencies are also classical.
  4. cYSTIC FIBROSISimage

  5. N-acetylcysteine (cleaves disulfide bonds in mucus)  + antipseudomonal prophylaxis (tobramycin/azithromycin) 

Bronchiectasis, meconium ileus, nasal polyps, failure to thrive, \

Cystic fibrosis: presenting signs CF PANCREAS:

Chronic cough and wheezing

Failure to thrive

Pancreatic insufficiency (symptoms of malabsorption like steatorrhea)

Alkalosis and hypotonic dehydration

Neonatal intestinal obstruction (meconium ileus)/ Nasal polyps

Clubbing of fingers/ Chest radiograph with characteristic changes

Rectal prolapse

Electrolyte elevation in sweat, salty skin

Absence or congenital atresia of vas deferens

Sputum with Staph or Pseudomonas (mucoid)

CF PANCREAS

  •  Chronic respiratory diseases occur*
  •  Failure to thrive, poor weight gain
  •  Pancreatic exocrine and endocrine insufficiency, Pulmozyme as treatment
  •  Autosomal recessive inheritance, metabolic Alkalosis
  •  Neonatal intestinal obstruction, meconium ileus, intussusception, volvulus
  •  Clubbing of fingers, Cholestasis, biliary Cirrhosis, …**
  •  Rectal prolapse
  •  Electrolyte excess in sweat like sweat Na+ and Cl-
  •  Azoospermia and infertility
  •  Staph aureus and pSeudomonas in sputum, Salty sweat

73N  on  July  24th   ·  reblog




478N  on  July  24th   ·  reblog



demandingdream:

the most annoying thing on earth is when nonvegans call vegan food gross like you are literally eating a dead animals flesh don’t fucking start w me


2405N  on  July  24th   ·  reblog



ironxwilled:

sovietxprincess:

If you’re a guy who likes looking at pictures of naked girls but loses respect for a girl if she posts a naked picture of herself, you can get lost

How many times can I reblog this


181018N  on  July  24th   ·  reblog



gr8cosplaytips:

gr8cosplaytips:

how do japanese chihuahuas say hello

konnichihuahua


12903N  on  July  24th   ·  reblog




When Raining Jane and I originally penned “A Beautiful Mess,” we had no idea we would ever be where we are now. But we certainly dreamed it, evident in the lyric, “We will fly like birds not of this earth.” This is truly how we feel right now in this shared experience, so much so that the new album cover donning 5 birds reflects that and is dedicated to our ongoing journey together. We thank you for being a part of this. And we thank you for lifting us up.

When Raining Jane and I originally penned “A Beautiful Mess,” we had no idea we would ever be where we are now. But we certainly dreamed it, evident in the lyric, “We will fly like birds not of this earth.” This is truly how we feel right now in this shared experience, so much so that the new album cover donning 5 birds reflects that and is dedicated to our ongoing journey together. We thank you for being a part of this. And we thank you for lifting us up.


35N  on  July  24th   ·  reblog
jason   



I Will Gobble You Up!
A Great Big Pile of Leaves

172N  on  July  24th   ·  reblog
tunes   




5924N  on  July  24th   ·  reblog




322391N  on  July  24th   ·  reblog




danny devito legit fucking tweeted this

danny devito legit fucking tweeted this


4259N  on  July  24th   ·  reblog




135771N  on  July  24th   ·  reblog



Ok so I think this is so so so freakin weird

I had a dream that I was in some city quarantined because someone had the bubonic plague

And I just remembered it so I decided to google bubonic plague just to refresh my memory as to what it was and I thought it was weird because why the heck would I dream about a historical disease??

Well it turns out a city in china WAS RECENTLY AND IS STILL BEING QUARANTINED BECAUSE A MAN DIED FROM THE BUBONIC PLAGUE




albumwallpapers:

Glocca Morra, Just Married

albumwallpapers:

Glocca Morra, Just Married


1142N  on  July  23rd   ·  reblog



shoegazevevo:

yeah i like the Smiths uve probably never heard of them… i wear crop tops and platform sandals .… smoke marlboros all the tim e… i love aliens and the 90’ s„.. got a flannel tied around my waist and two lil side braid s… i like looking at the sky…. . aestheti c


6498N  on  July  23rd   ·  reblog



pretty sure i’m taking the mcat again

grr


July  23rd   ·  reblog